Medications to Treat Anxiety Therapy is the best method to manage anxiety, however sometimes a short-term course medication may be necessary. Treatment options for anxiety include antidepressants and tranquilizers. SSRI antidepressants, such as citalopram (Celexa), Escitalopram (Lexapro) and sertraline (Zoloft), improve the communication between nerve cells in the brain, and
